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Autism

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[[File:Autismbrain.jpg|thumbnail|200px|right|Autism affects the [[amygdala]], [[cerebellum]], and multiple other parts of the brain.]]
'''Autism''' is a type of pervasive developmental disorder. It is characterized by difficulties with social interaction; difficulties with verbal communication, especially pragmatic language; difficulty processing nonverbal communication such as facial expression; intense, narrow interests; difficulty adjusting to changes in routine; and repetitive behaviors. Other signs include lack of eye contact, delayed or unusual play skills, hypo- or hyper-sensitivity to sensory stimuli, and anxiety.<ref>http://www.webmd.com/brain/autism/development-disorder?page=2</ref> It is usually detected by the time a child is four years old but in some cases, autism goes unnoticed into adulthood. There are many intelligent and talented autistic individuals.<ref>Temple Grandin, "Thinking in Pictures, Expanded Edition: My Life with Autism" amazon link httphttps://www.amazon.com/gp/product/0307275655/ref=wl_it_dp/103-3432247-4184629?ie=UTF8&coliid=I1CWNFSEUCIXQL&colid=49VN3HJC5OQK</ref> The term '''autism''' was first used in 1912.
Diagnoses of autism has increased from 1:10,000 in 1988 to as high as 1 in 150 people,<ref>httphttps://www.cdc.gov/ncbddd/autism/faq_prevalence.htm</ref> and it has been rising. Four times as many boys suffer from autism as girls.<ref name="Clinic Stats">http://www.iupui.edu/~psycdept/autism/autism.htm</ref> Among boys, 1 in 94 has the disorder. In New Jersey, which has the highest rate in the nation, 1 in every 60 boys has autism and 1 in every 94 children is affected. There is a seizure disorder in about one-third of those who have autism.<ref name="Clinic Stats"/>
Autism is said to exist on a "spectrum;" that is, there is a wide range of how this disorder affects people. Other pervasive developmental disorders on the "autism spectrum" include [[Asperger's syndrome]], Pervasive Developmental Disorder - Not Otherwise Specified (PDD-NOS), Childhood Disintegrative Disorder, and Rett's Syndrome. There are many degrees of functioning in individuals with autism. Because of this, all individuals diagnosed with autism will not exhibit the same characteristics, or exhibit them to the same degree.
Autism was first identified clinically in 1943 by Dr. [[Leo Kanner]]. Dr. Hans Asperger , in collusion with the [[Nazi Party]], also did some research into autism at about the same time and discovered Asperger's syndrome. As early as the 1990s, many intervention strategies, including Applied Behavioral Analysis ([[ABA therapy]]), were used to treat autism or mitigate its symptoms. Autism (especially high-functioning autism and Asperger syndrome) rights are promoted by the [[neurodiversity]] movement. The autism rights movement, also known as the autistic acceptance movement, is a social movement within the context of disability rights that emphasizes a neurodiversity paradigm, viewing the autism spectrum as a result of natural variations in the human brain rather than as a disease to be cured.
==How does autism develop?==
Although there have been no formal epidemiological studies, the evidence suggests that autism is rare in the economically developing continent of Africa and mainly exists within elite families.<ref name="Autism in Africa"/><ref>[http://www.ageofautism.com/2008/11/out-of-africa-a.html Out of Africa and Into Autism: More Evidence Illuminates the Somali Anomaly in Minnesota], By Mark F. Blaxill, AgeofAutism.com website (I don't agree with the anti-vaccine portion of the article)</ref> In addition, the traditional [[Africa]]n diet is healthier than many Western World invividuals' diets and Africa has some of the lowest obesity rates in the world.<ref>
*[httphttps://www.forbes.com/2007/02/07/worlds-fattest-countries-forbeslife-cx_ls_0208worldfat.html World's fattest countries]
*[http://www.todaysdietitian.com/newarchives/030612p26.shtml Traditional African diets are healthier than Western diets], Today's Nutrition</ref> Furthermore, Africa is a religious continent with high birth rates.
The American Amish have a low autism rate which may be due to their healthy and simple lifestyle, their genetic makeup or both.<ref>
*[httphttps://www.foxnews.com/health/2014/12/04/4-healthy-habits-to-steal-from-amish.html 4 healthy habits to steal from the Amish], Fox News Health, December 04, 2014
*"[http://www.internalmedicine.osu.edu/genetics/article.cfm?id=5307 Amish Have Lower Rates of Cancer, Ohio State Study Shows]". Columbus, OH: Ohio State University Medical Center. January 1, 2010. Retrieved January 6, 2010.
*Puffenberger, EG; Jinks, RN; Wang, H; Xin, B; Fiorentini, C; Sherman, EA; Degrazio, D; Shaw, C; Sougnez, C; Cibulskis, K; Gabriel, S; Kelley, RI; Morton, DH; Strauss, KA (Dec 2012). "A homozygous missense mutation in HERC2 associated with global developmental delay and autism spectrum disorder". Human Mutation 33 (12): 1639–1646
*Jackman, C; Horn, ND; Molleston, JP; Sokol, DK (Apr 2009). "Gene associated with seizures, autism, and hepatomegaly in an Amish girl". Pediatric Neurology 40 (4): 310–313.
*Alarcón, Maricela; Abrahams, Brett S.; Stone, Jennifer L.; Duvall, Jacqueline A.; Perederiy, Julia V.; Bomar, Jamee M.; Sebat, Jonathan; Wigler, Michael; Martin, Christa L.; Ledbetter, David H.; Nelson, Stanley F.; Cantor, Rita M.; Geschwind, Daniel H. (10 January 2008). "Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene". American Journal of Human Genetics 82 (1): 150–159</ref> Due to their high levels of physical activity, the Amish have low rates of obesity.<ref>
*[httphttps://www.foxnews.com/health/2014/12/04/4-healthy-habits-to-steal-from-amish.html 4 healthy habits to steal from the Amish], Fox News Health, December 04, 2014</ref>
David N. Brown indicated: "In March 2006, Drs. Kevin Strauss, Holmes Morton and others documented 9 autistic Amish children, which could raise the autism rate of the Lancaster Amish community Olmsted supposedly investigated to almost 1/5,000 which is still a fraction of the US average of 1/68."<ref>Puffenberger, EG; Jinks, RN; Wang, H; Xin, B; Fiorentini, C; Sherman, EA; Degrazio, D; Shaw, C; Sougnez, C; Cibulskis, K; Gabriel, S; Kelley, RI; Morton, DH; Strauss, KA (Dec 2012). "A homozygous missense mutation in HERC2 associated with global developmental delay and autism spectrum disorder". Human Mutation 33 (12): 1639–1646</ref><ref>Jackman, C; Horn, ND; Molleston, JP; Sokol, DK (Apr 2009). "Gene associated with seizures, autism, and hepatomegaly in an Amish girl". Pediatric Neurology 40 (4): 310–313.</ref><ref>Alarcón, Maricela; Abrahams, Brett S.; Stone, Jennifer L.; Duvall, Jacqueline A.; Perederiy, Julia V.; Bomar, Jamee M.; Sebat, Jonathan; Wigler, Michael; Martin, Christa L.; Ledbetter, David H.; Nelson, Stanley F.; Cantor, Rita M.; Geschwind, Daniel H. (10 January 2008). "Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene". American Journal of Human Genetics 82 (1): 150–159</ref>
=== Genetics ===
Some experts suspect that there is a genetic susceptibility to autism.<ref>http://healthland.time.com/2011/06/09/studies-new-clues-to-the-genetic-roots-of-autism/</ref><ref>httphttps://www.foxnews.com/health/2011/08/11/autism-adhd-share-genetic-similarities/</ref><ref>httphttps://www.latimes.com/health/la-he-autism-20110815,0,3154651.story</ref><ref>Happé F, Ronald A. The 'fractionable autism triad': a review of evidence from behavioural, genetic, cognitive and neural research. Neuropsychol Rev. 2008;18(4):287–304</ref><ref>Freitag CM. The genetics of autistic disorders and its clinical relevance: a review of the literature. Mol Psychiatry. 2007;12(1):2–22. doi:10.1038/sj.mp.4001896. PMID 17033636</ref> The genetics of this condition are not fully understood; perhaps caused by complex interactions between multiple genes which would account for the "spectrum" like differences in the severity of many cases <ref>http://66.102.1.104/scholar?hl=en&lr=&q=cache:7kMNqvTgRtoJ:www.ikhebeenvraag.be/mediastorage/FSDocument/52/Freitag-2.pdf+</ref><ref>httphttps://www.ncbi.nlm.nih.gov/pubmed/17764594</ref>
Simon Baron-Cohen, director of the Autism Research Centre at the [[University of Cambridge]] (U.K.) says that males and females are hardwired for different behavior, with boys tending to be stronger at mechanics, categorizing and systemizing information, mathematics, etc. and girls stronger at emotionalizing and empathizing. He has proposed that autism is merely an extreme version of the [[male brain type]], in which the (female) urge to empathize is nearly absent and the brain is almost entirely hardwired for the (male) tasks of systemizing.<ref>Baron-Cohen, Simon. ''The Essential Difference'', Basic Books 2003.</ref>
==Interventions and Treatments==
*Applied Behavioral Analysis (ABA) - This is a behavioral intervention which applies the study of behavioral analysis, as well as the tools of this study, toward assisting behaviors of social significance in individuals of many different populations, including children with autism.<ref>http://www.centerforautism.com/getting_started/aba.asp</ref> Applied behavior analysis is used to increase positive behaviors, decrease interfering behaviors, maintain positive behaviors, teach new skills, and generalize new positive behaviors across many different settings, not just in a restrictive classroom or therapy setting. Therapists begin by observing the behaviors of the individual, focusing on skills and behaviors to reinforce or teach, and identifying interfering behaviors to be minimized. They then develop an intervention plan to reinforce the positive behaviors and skills, by using a system of rewards when the individual receiving the therapy exhibits the behavior that the therapist wants to observe. As the individual incorporates more positive behaviors, the therapist may decrease or change the reinforcement as necessary. However Some Critics have said it can be harmful.
*Developmental, Individual difference and Relationship-based (DIR/Floortime) model - This is a relationship-based intervention, developed by Dr. Stanley Greenspan, which focuses on developing a connection with the individual with autism, emphasizing the role his or her interests, emotions, and preferences play in developing an effective treatment.<ref>http://www.icdl.com/dirFloortime/overview/index.shtml</ref> This model emphasizes individual differences in children with autism, and requires caregivers and therapists to approach each child accordingly. It begins with understanding the child's developmental stage, understanding the ways in which the child understands and learns information and processes sensory stimuli, and developing relationships between the child and his or her caregivers and therapists, who tailor their affect and interactions to the child's needs. This model especially emphasizes the importance of parents and caregivers in the process of their child's treatment, because of their unique relationship to the child.
...some people were angry that I seemed to suggest that atheists were antisocial weirdos. Well, [http://www.gnxp.com/blog/2007/08/religiosity-and-personality-how-are.php there is some data to back that up].<ref>[http://blogs.discovermagazine.com/gnxp/2011/09/what-atheism-and-autism-may-have-in-common/ What atheism and autism may have in common] By Razib Khan, September 19, 2011</ref>}}
 
==Autism and vaccinations: is there a link?==
On April 29, 2019, in a speech on the floor of the [[Louisiana]] State Senate, [[John Milkovich]], a strongly pro-life [[Democratic Party|Democrat]] from [[Shreveport]], flatly declared that [[vaccination]]s are linked to autism. In his remarks, Milkovich recalled that “autism did not exist” when he was growing up in [[Montana]]: "Did you know tissue from aborted babies is now used in vaccines. Did you know that vaccines use [[aluminum]], which is shown to be a neurotoxin? Did you know vaccines in America [are] preserved often with [[mercury]], which is beyond neurotoxic?”<ref name=autism>{{cite web|url=https://www.theadvocate.com/baton_rouge/news/politics/article_0c13f5ea-6ad7-11e9-876a-b3|title=Louisiana senator links vaccines, autism on Senate floor; officials say 'myth' causes measles resurgence|author=Sam Karlin|date=April 29, 2019|publisher=''The Baton Rouge Advocate''|accessdate=April 30, 2019}}</ref> Dr. Joe Kanter, the assistant state health officer, disputed Milkovich's claim as "a myth." Kanter said that the issue of autism and vaccination has been “incredibly well studied”, and no correlation has been found.<ref name=autism/>
==See also==
*[[Symptoms of autism]]
*[[Autism Society of America]]
*[[Neurodiversity]]
==References==
==External links==
#http://www.autismspeaks.org/
#http://www.autismdigest.com/
#http://www.nationalautismassociation.org/