Talk:Letter to PNAS

It's an excellent draft, DinsdaleP. I made a few minor revisions above. After others improve this, then I'll plan on sending it to PNAS later this week. —The preceding unsigned comment was added by Aschlafly (talk)

I like it. I'll sign my name to it when the time comes.--DamianJohn 09:35, 22 July 2008 (EDT)

(unindent)

Thanks for the feedback - When applying changes, please keep in mind that the "Text" section in the final version needs to be 250 words or less. If there are important points to add that would exceed this limit, they could be added to the main Flaws in Richard Lenski Study article instead since PNAS is being asked to respond to the full list there, and not just the summary. --DinsdaleP 09:47, 22 July 2008 (EDT)

I think if i would have presented some draft of that quality to my supervisor i think i would not have reached the door of his office alive and in one piece. It starts with the fact that the correct citation of the article is missing. Please use the appropriate form, inclucing journal number and page. Please have a look at other PNAS Letters. Restate the central issue you criticise in the first sentence, then explicitely describe what your claim about the same issue is and state using what method you come to your conclusion. Keep a neutral tone. Don't make requests. It is obvious that the original author should respond (please look at PNAS for examples of responses, which are published at the same location). Plese fill in your numbers and precise arguments at the points where i left the dots in the following suggestion (Please note that nothing of this is my opinion, i just tried to rephrase your opinions in a way that they have the chance to be exposed to a broader view - i skipped tyhe details, because i will not rephrase your arguments, just the structure):

Recently ...... inferred from their experiments (1) that ...... . We analyzed the statistical analysis in terms of ..... and conclude that several variables do not scale as .... . Using hypothesis tests under such circumstances is, in our opinion, ...... , and we do not understand how the authors of the original publication ..... their results.

The replay experiments yield an ..... scaling with .... . We do not find a consistent value of ..... between the experiments. Furthermore the statistical deviation due to ...... in each sample set does not allow to infer ..... with a sufficient precision. This lack of scaling makes, in our opionion a constant or random source of contamination a likely explanation for a random observation of the ...... dependence of the mutation rate claimed in the paper. The following calculation supports this hypothesis: ....... .

Furthermore we point out that Fig. ... contains a serious disagreement with .....: while the data would suggest ..... from gen. ..... the figure suggests .....

We find the material cited in the original article (2)...(n) about the same long-time experiment not to describe the following procedures and experimental constants in a way accessible to us: Handling of ..., contamination rates of ...., and ..... We would kindly ask the authors to clarify these issues. --Stitch75 12:48, 22 July 2008 (EDT)

No offense taken. I have no experience in these types of submissions, and would appreciate it if you could restructure the submission improve the quality while adhering to the 250-word limit. As I suggested above, it makes the most sense to incorporate these revisions into the main page for this article, where length is not an issue. --DinsdaleP 12:52, 22 July 2008 (EDT)

I realized that you have obviously not much experience in it; getting the right tone for a scientific publication is hard and i had to try it quite some times on conferences and i still dont get it right sometimes - and from what you said seem to be a student. Sadly, it is against my conviction to rephrase the original arguments in the right way because it would make me an co-author of argumentations i strongly object. In case you did not realize it, helping here to get the structure right doesn't mean i agree - actually the two reasons i would like to see it published is because then the (wrong) idea that scientific journals are not accepting criticism could be obviously be put aside and because i would like to see the needed scientific rigorousity applied to the arguments presented here, because this would put this discussion onto a scientific basis. Quite frankly - i am a liberal by the standards of this site. But i believe the discussion must be carried out with all respect to define the borders of science. The more effective the discussion is carried out, the better the outcome will be. I am willing to listen, as i have proven here, even when beeing treated by people like Mr. Schlafly as if I would be one of his students, while evaluating his qualification in natural sciences quickly shows that i more likely could supervise him in the issues he discusses here (which is something he has proven all along). Regarding that, i am close to giving up, but nevertheless i have seen that a lot of conservatives actually are willing to lead this discussion in a scientific way, which is something, which fulfills me with hope. I recommend you not to fight a fight in where you don't understand the arguments. Don't pick up arguments from others. If you can not fill in the missing words, numbers and arguments in my text, i cant help you. I see what Mr. Schlafly believes, however i do not know how to get the calculation right to support his hypothesis (random or contant mutation rate) - and, this is most likely not because of a lack of statistical knowledge. The only way i would see is to use the rudest form of descriptive statistics and agreggate the data in a very specific way, while ignoring the structure of the experiment - and ignoring the fact that the authors pointed out the problem they see and adressed them. So i can only give oy a few hints (maybe i can form a short contibution to conservapedia; i am just thinking about the title):

If you claim something is wrong, put your opposing claim in a positive formulation, with a supporting calculation, in contrast . Even if the calculation is simple, this is very important to provide it. E.g. we estimate a rate of x+-y per z for dataset N, in which we aggregated generations a,b,c,d, etc .... In the end, you should either prove a mathematical mistake (which was not done) or shoe you hypothesis is more likely.

Don't be rude. You are not the referee and you are not member of a commitee to examine scientific misbehaviour. Dont act like one (and even referees have a friendlier tone usually). Dont act like an personal enemy either. Don't ask for retraction of the article. It is up to the author to make the conclusion respond or retract. This happens more often than you may think as a response to an critisism (actually it's fun to read the "reply section" of scientific journals - sometimes you find things like: "yes, the commenter was right we copied the paper and retract it"). And you are never requesting, but you are kindly asking. Everybody understands that "kindly asking" does not mean "kindly asking" in this context.

Always give full and specific citations which back your claims. Give it in the form required by the specific journal. General citations like "materials on his website" will make your text bein trown out in the editorial screening (because you can not expect that somebody read trough all information to find something backing you claim - this is your job). See for specific styles [http://en.citizendium.org/wiki/Citation_style]. Ypu may even reference a page/paragraph/eq/figure number to point the reader to what you mean (for papers longer than 4 pages i usually do that).

Run a style checker over your text to eliminate common style mishaps.

Most important: go to your university library. Take the time to just read a few PNAS Letters and replys, and the original articles (Try to finde some with an easy understandable subject). Understanding how these are written and how authors usually reply will help you to get your one right. You are writing against somebody who has twenty years of experience in a field of publishing in natural sciences. You seem to have little experience and Andrew Schlafly, honestly, neither. This game is an uphill battle and unfair game anyway. Make sure you maximize your chances by understanding the rules of the game.

Focus on a single you are sure about. It is better to present one claim well that two claims badly.

Good luck. You will need it. --Stitch75 14:22, 22 July 2008 (EDT)

"Stitch75", you seem to think that the truth depends on whether PNAS accepts it. It doesn't. Lenski's paper is badly flawed regardless of whether he admits it, PNAS admits it, or you admit it. That's the beauty of the truth: it doesn't require admission by anyone. I'm fine with Lenski and PNAS refusing to admit the flaws in their paper. After all, if they really cared about quality then I doubt they would have published their flawed paper after merely 14 days or less of peer review.--Aschlafly 15:38, 22 July 2008 (EDT)

I tend to agree with you Andy. I say we get this thing sent to PNAS and see what happens. If they refuse to answer it then we know what that means, and if they thumb their noses at you that's fine too. However I have a little more faith than you in the system and I hold out hope that they'll respond to our queries. Anyway lets get this thing sent. --DamianJohn 15:50, 22 July 2008 (EDT)

(unindent)

I'd like to thank Stitch75, because he took the time to explain his points constructively, and I learned something from them. (I'm actually an IT Specialist in my 40's, not a full-time student, but learning is a never-ending process and I appreciated the lesson). I consider myself bound by the same ethical constraints on editing that he mentioned, because these objections to Lenski's work are Mr. Schlafly's, not my own. I tend to believe that the Lenski experiment was properly executed, but I'm a strong believer in the scientific process, and Mr. Schlafly's objections deserve a fair hearing whether one believes in them or not. My contribution is to help in the process of getting these objections to the proper forum, namely PNAS, and leaving the response up to them. --DinsdaleP 16:20, 22 July 2008 (EDT)

Stich has given you brilliant advice, and you throw it away. He has told you that your letter will not get published, and it will have nothing to do with it's content. And when it doesn't get published you will claim it as a victory. If you take his advice and continue to take it, you will make it so no one can simply claim your letter wasn't accepted because it didn't match the criteria set out for letters to PNAS. Now if you have a well written and correctly laid out letter, and then it isn't published, at least you have a leg to stand on.

As a lawyer I would have expected you to understand that certain documents need to be written in set styles, and obey certain rules. Have you published anything (this isn't meant to be derogatory, it's a geniune request), I am positive you must have done so. When you did your citations would have had to be correctly arranged, and many other rules obeyed. Law suits are written up in a set style, and no one would dream of simply scribbling a note and saying check out this website, and expect to be taken seriously. So why do you expect a scientific journal to accept whatever you send them? Follow the procedures, then you have a right to complain if nothing happens. Raggs 10:12, 25 July 2008 (EDT)

How about this one

I'm not going to say I know much about the science but I made this suggestion a few days ago (in the article page). It is certainly a lot shorter, and I think a little more polite. What do you think Andy