Difference between revisions of "PrPres"
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PrP<sup>res</sup>, also known as PrPSc, is a [[prion]] [[isoform]] of [[PrP]], or PrPc. It is the sole cause of [[transmissible spongiform encephalopathy]]. The name comes from 'prion protein resistant', meaning it is resistant to [[proteinase K]]. PrPres is able to convert healthy PrPc into copies of itself. These prions are neurotoxic. | PrP<sup>res</sup>, also known as PrPSc, is a [[prion]] [[isoform]] of [[PrP]], or PrPc. It is the sole cause of [[transmissible spongiform encephalopathy]]. The name comes from 'prion protein resistant', meaning it is resistant to [[proteinase K]]. PrPres is able to convert healthy PrPc into copies of itself. These prions are neurotoxic. | ||
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Latest revision as of 11:14, November 7, 2026
PrPres, also known as PrPSc, is a prion isoform of PrP, or PrPc. It is the sole cause of transmissible spongiform encephalopathy. The name comes from 'prion protein resistant', meaning it is resistant to proteinase K. PrPres is able to convert healthy PrPc into copies of itself. These prions are neurotoxic.