Quinacrine
Quinacrine, also known as mepacrine or acrichine, belongs to the class of organic compounds known as acridines. These are organic compounds containing the acridine moiety, a linear tricyclic heterocycle which consists of two benzene rings joined by a pyridine ring. Quinacrine is used as a treatment for malaria, and as an antibiotic. Quinacrine is mostly known for its failure in drug trials for transmissible spongiform encephalopathy diseases. It is a small molecule drug, and was shown in lab tests to slow down or stop prion misfolding. However, in humans, the same effect was not observed. In addition, it caused liver issues in TSE patients. However, some people still believe it works. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus.