Difference between revisions of "Chlorpromazine"
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| − | '''Chlorpromazine''', marketed in the US as '''Thorazine''', is a typical [[antipsychotic]] drug and was the first antipsychotic to be synthesized, circa December 1950. Despite the drug's age, it still holds a place in the modern treatment of psychosis, though it is now used less often than newer antipsychotics (such as quetiapine). | + | '''Chlorpromazine''', marketed in the US as '''Thorazine''', is a typical [[antipsychotic]] drug and was the first antipsychotic to be synthesized, circa December 1950. Despite the drug's age, it still holds a place in the modern treatment of psychosis, though it is now used less often than newer antipsychotics (such as [[quetiapine]]). |
== Indications == | == Indications == | ||
| Line 5: | Line 5: | ||
*[[Schizophrenia]] | *[[Schizophrenia]] | ||
| − | *Severe mania in people with bipolar disorder | + | *Severe [[mania]] in people with bipolar disorder |
*Uncontrollable hiccups | *Uncontrollable hiccups | ||
*As a low-dose and short-term treatment for nausea and vomiting | *As a low-dose and short-term treatment for nausea and vomiting | ||
| Line 15: | Line 15: | ||
*Drowsiness | *Drowsiness | ||
*Dizziness | *Dizziness | ||
| − | *Orthostatic hypotention | + | *[[Orthostatic hypotention]] |
*Worsening of symptoms upon stopping treatment with the drug | *Worsening of symptoms upon stopping treatment with the drug | ||
Revision as of 22:25, September 13, 2015
Chlorpromazine, marketed in the US as Thorazine, is a typical antipsychotic drug and was the first antipsychotic to be synthesized, circa December 1950. Despite the drug's age, it still holds a place in the modern treatment of psychosis, though it is now used less often than newer antipsychotics (such as quetiapine).
Indications
Chlorpromazine is indicated for the treatment of:
- Schizophrenia
- Severe mania in people with bipolar disorder
- Uncontrollable hiccups
- As a low-dose and short-term treatment for nausea and vomiting
Side effects
Like most antipsychotics, chlorpromazine has a number of side effects, while most are common, some can be more serious, possibly resulting in Death. Side effects are:
Common
- Drowsiness
- Dizziness
- Orthostatic hypotention
- Worsening of symptoms upon stopping treatment with the drug
Rare
- Neuroleptic malignant syndrome, a potentially deadly condition in which the drug disrupts the body's thermal regulation system, causing high fever and delirium.
- Tardive dyskinesia, a potentially incurable neurologic disorder, usually reported with long-term use.