Difference between revisions of "Point mutation"
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| − | A point mutation is the most limited type of mutation, whereby a single base nucleotide is replaced with another nucleotide. Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair. | + | A point [[mutation]] is the most limited type of mutation, whereby a single base [[nucleotide]] is replaced with another nucleotide. Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair. |
| − | The sickle-cell disease | + | The sickle-cell disease is caused by a single point mutation in the beta hemoglobin gene, whereby a GAG codon is converted into GTG. The GTG then mistakenly encodes the amino acid valine instead of glutamic acid. |
Revision as of 02:19, July 14, 2007
A point mutation is the most limited type of mutation, whereby a single base nucleotide is replaced with another nucleotide. Sometimes the expression "point mutation" can also include the addition or subtraction of a single base pair.
The sickle-cell disease is caused by a single point mutation in the beta hemoglobin gene, whereby a GAG codon is converted into GTG. The GTG then mistakenly encodes the amino acid valine instead of glutamic acid.