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Talk:Point mutation (view source)
Revision as of 02:08, February 12, 2009
, 02:08, February 12, 2009→Genetic Information: Replies to Able806 and MattL
:: Rather a late response, and pointless, given the merge, but I was primarily correcting the wording to what the reference was actually claiming. [[User:Philip J. Rayment|Philip J. Rayment]] 09:41, 11 February 2009 (EST)
:: Rather a late response, and pointless, given the merge, but I was primarily correcting the wording to what the reference was actually claiming. [[User:Philip J. Rayment|Philip J. Rayment]] 09:41, 11 February 2009 (EST)
:::Thank you, I had guessed that after reading through the reference a bit. Something I have to ask, the papers published by the ICR and such groups, are they available for scientific review? I would like to research their position about genetic information particularly in relation to increase of information. From what I know of molecular genetics and information molecules, the ability for information to be increased through mutation is possible and has been observed. I would like to research the claims of ICR and such as to why they believe these examples fail. If you could be of assistance with this I would greatly appreciate it.--[[User:Able806|Able806]] 10:33, 11 February 2009 (EST)
:::Thank you, I had guessed that after reading through the reference a bit. Something I have to ask, the papers published by the ICR and such groups, are they available for scientific review? I would like to research their position about genetic information particularly in relation to increase of information. From what I know of molecular genetics and information molecules, the ability for information to be increased through mutation is possible and has been observed. I would like to research the claims of ICR and such as to why they believe these examples fail. If you could be of assistance with this I would greatly appreciate it.--[[User:Able806|Able806]] 10:33, 11 February 2009 (EST)
::::: Almost all such papers are ''available'' for anybody (scientists or otherwise) to "review" (read and comment on), as they have been published. But is that what you are asking? Are you asking about peer review? Papers published in the ''Journal of Creation'' and the ''CRS Quarterly'' are peer-reviewed. I don't know about ICR papers, but I suspect that ones published in ''Impact'' would be also.
::::: [http://creationontheweb.com/content/view/3012/ This page] list a number of layman's articles and technical papers which cover the [[information]] aspect in more detail. Also, Werner Gitt's ''In the Beginning was Information'' is [http://www.sedin.org/propeng/informat.htm available online].
::::: [[User:Philip J. Rayment|Philip J. Rayment]] 21:08, 11 February 2009 (EST)
::::A good, information-increasing point mutation that comes to mind is the [https://content.nejm.org/cgi/content/extract/350/20/2096 LRP5 substitution], which "[enhances] skeletal mass without causing complications of osteopetrosis". Some users may be confused by the term "High-Bone-Mass Disease". If so, please see the medical definition of [http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/three/000030493.htm disease]. Some people are unwilling to open their minds to this being an instance of increased information. If that is the case, please proffer a definition of information in this context. [[User:MattL|MattL]] 10:48, 11 February 2009 (EST)
::::A good, information-increasing point mutation that comes to mind is the [https://content.nejm.org/cgi/content/extract/350/20/2096 LRP5 substitution], which "[enhances] skeletal mass without causing complications of osteopetrosis". Some users may be confused by the term "High-Bone-Mass Disease". If so, please see the medical definition of [http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/three/000030493.htm disease]. Some people are unwilling to open their minds to this being an instance of increased information. If that is the case, please proffer a definition of information in this context. [[User:MattL|MattL]] 10:48, 11 February 2009 (EST)
::::: Most claims of information-increasing mutations turn out to nothing of the sort, and the linked extract of this paper does not have enough information to say one way or the other in this case. However, a mutation that merely changes the ''quantity'' of something (mass in this case) is likely ''not'' an information-increasing mutation, just like a cake recipe that has a "mutation" in the quantity of flour is not adding new ''information''. [[User:Philip J. Rayment|Philip J. Rayment]] 21:08, 11 February 2009 (EST)
:Can you write some simple introductory material about the [[genome]], [[genome expression]], [[regulatory protein]]s, [[gene regulation]], and [[mutation]]? Nearly all of our readers need to know about the basics before they can learn about advanced topics such as [[point mutation]]. --[[User:Ed Poor|Ed Poor]] <sup>[[User talk:Ed Poor|Talk]]</sup> 09:39, 4 February 2009 (EST)
:Can you write some simple introductory material about the [[genome]], [[genome expression]], [[regulatory protein]]s, [[gene regulation]], and [[mutation]]? Nearly all of our readers need to know about the basics before they can learn about advanced topics such as [[point mutation]]. --[[User:Ed Poor|Ed Poor]] <sup>[[User talk:Ed Poor|Talk]]</sup> 09:39, 4 February 2009 (EST)