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==Rosalind Franklin controversy==

==Rosalind Franklin controversy==

His personal and informal account of this discovery "The Double Helix"  aroused some controversy with its frank account of the fiercely competitive nature of scientific research. In particular, he revealed that an important component of the breakthrough was the work of [[Rosalind Franklin]], and her unpublished experimental results were used without her knowledge or permission. Franklin died before the Nobel Prize was awarded.

His personal and informal account of this discovery "The Double Helix"  aroused some controversy with its frank account of the competitive nature of scientific research. In particular, he revealed that the X-ray diffraction pattern image in "Photo 51", a image created by [[Rosalind Franklin]]'s team, informed him of the alpha helix structure of the DNA molecule. After Franklin had announced her plans to leave the Kings College lab, Watson was shown this image by Wilkins. Wilkins had concluded that Franklin would appropriately be leaving her data to her successors at the lab. Neither Watson nor Wilkins opted to contact Franklin for permission, not did they inform her later of their action. Franklin died before the Nobel Prize was awarded.

==Final moment of great insight==

==Final moment of great insight==

Watson and Crick worked in a office aggregating and integrating all the known knowledge that they could about what was then known about DNA chemistry. Watson had his great [[insight]] at their Cavendish office on February 28, 1953. He had constructed the flat cardboard models of the four base pairs. The [[base pair]]s consisted of purines adenine and guanine and the pyrimidines thymine and cytosine. He began trying different orientations of them, flipping them over and sliding them around on the office table. He saw a potential for hydrogen bonding between the adenine and thymine. He then oriented the guanine and cytosine in a similar way and saw the same hydrogen bonding pattern. He then compared the two aggregates and saw that they were similar in shape and he soon realized that they would be appropriate as perhaps rungs on a ladder and quickly became confident that he had made the final breakthrough.<ref>https://www.dnalc.org/view/15492-Discovering-the-double-helix-structure-of-DNA-James-Watson-video-with-3D-animation-and-narration.html</ref>

Watson and Crick worked in a office aggregating and integrating all the known knowledge that they could about what was then known about DNA chemistry. Watson had his great [[insight]] at their Cavendish office on February 28, 1953. He had constructed the flat cardboard models of the four base pairs. The [[base pair]]s consisted of purines adenine and guanine and the pyrimidines thymine and cytosine. He began trying different orientations of them, flipping them over and sliding them around on the office table. He saw a potential for hydrogen bonding between the adenine and thymine. He then oriented the guanine and cytosine in a similar way and saw the same hydrogen bonding pattern. He then compared the two aggregates and saw that they were similar in shape and he soon realized that they would be appropriate as perhaps rungs on a ladder and quickly became confident that he had made the final breakthrough.<ref>https://www.dnalc.org/view/15492-Discovering-the-double-helix-structure-of-DNA-James-Watson-video-with-3D-animation-and-narration.html</ref>

{{DEFAULTSORT:Watson,James}}

{{DEFAULTSORT:Watson,James}}

[[Category:Geneticists]]

[[Category:Geneticists]]

[[Category:Nobel laureates in Physiology or Medicine]]

[[Category:Nobel laureates in Physiology or Medicine]]