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| − | The '''HPV vaccine''' exists as 2 products, Gardasil (marketed by [[Merck]] and protecting against types 6, 11, 16 and 18 of the [[HPV|human papillomavirus]]) and Cervarix (marketed by [[GlaxoSmithKline]] and protecting against types 16 and 18 only). | + | The '''HPV vaccine''' exists as 2 products, Gardasil (marketed by [[Merck]] and protecting against types 6, 11, 16 and 18 of the [[HPV|human papillomavirus]]) and Cervarix (marketed by GlaxoSmithKline and protecting against types 16 and 18 only). |
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| | Genital warts are most commonly associated with HPV–6 and HPV–11. HPV types 16 and 18 together are found in about 70 percent of cervical cancers. <ref>National Cancer Institute: Human Papillomaviruses and Cancer: Questions and Answers [http://www.cancer.gov/cancertopics/factsheet/Risk/HPV]</ref> | | Genital warts are most commonly associated with HPV–6 and HPV–11. HPV types 16 and 18 together are found in about 70 percent of cervical cancers. <ref>National Cancer Institute: Human Papillomaviruses and Cancer: Questions and Answers [http://www.cancer.gov/cancertopics/factsheet/Risk/HPV]</ref> |
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| − | Only about 3% of women are infected in their lifetime by these four types of HPV (Types 6, 11, 16, 18) targeted by the vaccine.<ref name="JAMA">This was confirmed by a study published February 28, 2007 in the Journal of the American Medical Association, JAMA 297(8):813-819, February 28, 2007. "HPV vaccine types 6 and 11 (low-risk types) and 16 and 18 (high-risk types) were detected in 3.4% of female participants ...."[http://jama.ama-assn.org/cgi/content/full/297/8/813]</ref> The vaccine is very expensive and has been associated with severe adverse reactions, including paralysis.<ref>[http://www.telegraph.co.uk/health/healthnews/3758983/Schoolgirl-12-paralysed-after-receiving-cervical-cancer-jab.html 12-year-old paralyzed]</ref> | + | Only about 3% of women are infected by these four types of HPV (Types 6, 11, 16, 18) targeted by the vaccine.<ref name="JAMA">This was confirmed by a study published February 28, 2007 in the Journal of the American Medical Association, JAMA 297(8):813-819, February 28, 2007. "HPV vaccine types 6 and 11 (low-risk types) and 16 and 18 (high-risk types) were detected in 3.4% of female participants ...."[http://jama.ama-assn.org/cgi/content/full/297/8/813]</ref> The vaccine is very expensive and has been associated with severe adverse reactions, including paralysis.<ref>[http://www.telegraph.co.uk/health/healthnews/3758983/Schoolgirl-12-paralysed-after-receiving-cervical-cancer-jab.html 12-year-old paralyzed]</ref> |
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| | The HPV vaccine does not protect against other sexually transmitted diseases (e.g., [[chlamydia]], [[herpes]], [[hepatitis]], [[trichomoniasis]], [[gonorrhea]], [[syphilis]], [[HIV]], [[AIDS]], etc.), and the vaccine is not recommended for use in pregnant women or girls.<ref>http://www.merck.com/product/usa/pi_circulars/g/gardasil/gardasil_pi.pdf</ref> | | The HPV vaccine does not protect against other sexually transmitted diseases (e.g., [[chlamydia]], [[herpes]], [[hepatitis]], [[trichomoniasis]], [[gonorrhea]], [[syphilis]], [[HIV]], [[AIDS]], etc.), and the vaccine is not recommended for use in pregnant women or girls.<ref>http://www.merck.com/product/usa/pi_circulars/g/gardasil/gardasil_pi.pdf</ref> |