Ockham's Razor is a principle that can loosely be described as the simplest explanation is the one that is probably correct.
Ockham's Razor is one of the most widely used ontological principles in all fields of applied logic, most notably philosophy, theology, and systemology. It is attributed to William of Ockham, an English Franciscan Friar who lived in the late thirteenth and early fourteenth centuries. Briefly, it can be stated as follows:
- "From any set of equally probable explanations, we should assume the one which makes the fewest fundamental assumptions is correct, until we have reason to believe otherwise"
This is different from the shortest explanation, the shortest logical argument, and the simplest explanation, and the razor is often incorrectly quoted and/or applied. Some people have argued that these criteria qualify as better principles than the razor.
Occam's razor is a guiding principle. That is, it says that the explanation with the fewest assumptions is to be preferred, not is correct. The explanation with the fewest assumptions can turn out to be the wrong explanation.
Ockham's razor can be illustrated by the following common example. A tree is found uprooted in the middle of a field with no apparent cause. Two people offer competing hypotheses for how this occurred. Person A says that there must have been a storm last night, which combined with heavy rainfall the previous day, resulted in the uprooting of the tree. Person B says that last night aliens visited the planet Earth, and uprooted the tree as a message to mankind. There is no way of determining which of these hypotheses is correct after the fact, but as A's hypothesis makes far fewer fundamental assumptions (basically that the planet Earth has weather) than B's hypothesis (basically that aliens exist, have a way of finding humans in the cosmos, have a way of traversing space to reach our planet, could topple such a tree without being noticed, and so forth), we should assume A is correct and that a storm felled the tree unless B can provide some other evidence to support their claim.
Use by atheists
Among its practical applications, Occam's Razor has been used by atheists to argue against the existence of God. Let us take for an example the origin of intelligent life on Earth. One possibility for intelligent life is naturalistic evolution via natural selection. A second possibility is that God used evolution as His means of creation. Occam's Razor allows us to eliminate God from the hypothesis, since the idea is an unnecessary additional assumption. The 'simpler' explanation (that which makes fewer fundamental assumptions) is that God had nothing to do with the development of Intelligent Life and that it came about as a result of natural processes. Therefore, the earlier explanation is the most reasonable to believe.
It is, however, important to note that Ockham himself did not accept this reasoning; indeed, he considered the existence of God and the authority of Scripture to be truths which trumped the principle. While Occam's Razor is frequently articulated as "The simplest explanation is to be preferred," what he actually said was "For nothing ought to be posited without a reason given, unless it is self-evident (literally, known through itself) or known by experience or proved by the authority of Sacred Scripture." 
Use by Christians
The problem with the atheist example above is that it assumes that naturalistic evolution can explain the origin of intelligent life. Most theists would argue that God is not an unnecessary additional assumption, but a necessary additional assumption. Creationists would further argue that evolution is an unnecessary additional assumption—If you assume that God could create life, there is no need to assume that He needed to use evolution to do so.
Christian apologist William Lane Craig also has used Occam's razor to argue against polytheism. He argues that the Kalam Cosmological Argument argues against atheism, and that Occam's Razor would only require the existence of one god. 
- Occam's razor (The Skeptic's Dictionary).
- Grigg, Russell, Occam’s Razor and creation/evolution 22nd May 2007 (Creation Ministries International).
- Strobel, Lee. The Case for a Creator. Zondervan 2004
- The Skeptic's Dictionary
- Strobel, 2004