Stan Smith is a patriotic conservative republican agent of the CIA and father of two kids. His wife Francine and his son Steve support his politics. But his daughter Hayley is a liberal atheist Hippie. In addition Klaus, a gold fish with an exchanged brain of a German man, and the alien Roger live with the family.
In the episode Lincoln Lover Stan identically becomes involved with a Gay Republican Group and over time comes to support the inclusion of homosexuals in the Republican Party. In American Dream Factory it supports illegal aliens.